Question · asked by 1 review

Hyperbaric oxygen therapy (HBO) following extractions vs penicillin G: Adverse effects

Population
Adults with head and neck cancer undergoing curative or adjuvant radiotherapy (at risk of osteoradionecrosis of the jaws)
Intervention
Hyperbaric oxygen therapy (HBO) following extractions
Comparison
penicillin G
Outcome
Adverse effects

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Hyperbaric oxygen therapy (HBO) following extractions vs Perioperative antibiotic prophylaxis (penicillin G) following extractions
Adverse effects · Adults with head and neck cancer undergoing curative or adjuvant radiotherapy (at risk of osteoradionecrosis of the… · 6 months
Interventions for preventing osteoradionecrosis of the jaws in adults receiving head and neck radiotherapy (2019) · Cochrane All outcomes
Adverse effects were an outcome of interest in the study conducting this comparison, however no mention was made of the presence or absence of any adverse events1 study · 74 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Interventions for preventing osteoradionecrosis of the jaws in adults receiving head and neck radiotherapy
2019 · Cochrane All outcomes
2019-11Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.