Question · asked by 1 review

Topiramate plus ASMs vs placebo plus ASMs: Number of participants with adverse events leading to study discontinuation

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Topiramate plus ASMs vs placebo plus ASMs
Number of participants with adverse events leading to study discontinuation · Lennox‐Gastaut syndrome, any age
Anti‐seizure medications for Lennox‐Gastaut syndrome (2021) · Cochrane Headline outcomes only
no estimate extracted1 study · 98 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Anti‐seizure medications for Lennox‐Gastaut syndrome
2021 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.