Question · asked by 1 review
Hydrocortisone plus hyaluronidase (intralesional) vs Intralesional steroid plus hyaluronidase injections: Maximal mouth opening (interincisal distance)
- Population
- People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)
- Intervention
- Hydrocortisone plus hyaluronidase (intralesional)
- Comparison
- Intralesional steroid plus hyaluronidase injections
- Outcome
- Maximal mouth opening (interincisal distance)
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Hydrocortisone plus hyaluronidase (intralesional) vs Triamcinolone plus hyaluronidase (intralesional) Maximal mouth opening (interincisal distance) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF) Interventions for managing oral submucous fibrosis (2024) · Cochrane All outcomes | Singh 2010 (hydrocortisone+hyaluronidase 50 vs triamcinolone+hyaluronidase 50): mouth opening reported categorically (trismus) rather than as continuous data, precluding quantitative analysis; authors found no… | 1 study · 100 participants | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Interventions for managing oral submucous fibrosis 2024 · Cochrane All outcomes | 2022-09 | Not listed | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- Hydrocortisone plus hyaluronidase (intralesional) vs Placebo or no active treatment · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of… · 1 review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.