Question · asked by 1 review

Dexamethasone plus nystatin (adjunctive antifungal) vs dexamethasone: Clinical resolution

Population
People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment
Intervention
Dexamethasone plus nystatin (adjunctive antifungal)
Comparison
dexamethasone
Outcome
Clinical resolution

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Dexamethasone plus nystatin (adjunctive antifungal) vs Dexamethasone alone
Clinical resolution · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment
Interventions for treating oral lichen planus: corticosteroid therapies (2020) · Cochrane All outcomes
Wei 2003: no difference in clinical resolution between dexamethasone with vs without nystatin (very low-certainty)1 studyVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Interventions for treating oral lichen planus: corticosteroid therapies
2020 · Cochrane All outcomes
2019-02Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.