Question · asked by 1 review

Inhaled tobramycin (TNS) (28 days) vs TNS (56 days): Adverse effects of antibiotics

Population
adults and children with cystic fibrosis and a positive microbiological isolate of P aeruginosa from a respiratory tract specimen
Intervention
Inhaled tobramycin (TNS) (28 days)
Comparison
TNS (56 days)
Outcome
Adverse effects of antibiotics

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Inhaled tobramycin (TNS) (28 days) vs TNS (56 days)
Adverse effects of antibiotics · adults and children with cystic fibrosis and a positive microbiological isolate of P aeruginosa from a respiratory…
Antibiotic strategies for eradicating Pseudomonas aeruginosa in people with cystic fibrosis (2023) · Cochrane Headline outcomes only
no estimate extracted1 study · 77 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Antibiotic strategies for eradicating Pseudomonas aeruginosa in people with cystic fibrosis
2023 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.