Question · asked by 1 review

Pentoxifylline vs multivitamin and mineral supplement: Maximal mouth opening (interincisal distance)

Population
People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)
Intervention
Pentoxifylline
Comparison
multivitamin and mineral supplement
Outcome
Maximal mouth opening (interincisal distance)

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Pentoxifylline vs Multivitamin
Maximal mouth opening (interincisal distance) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)
Interventions for managing oral submucous fibrosis (2024) · Cochrane All outcomes
Rajendran 2006 (pentoxifylline 14 vs multivitamins 15): reported increased interincisal distance in the pentoxifylline group but no baseline data, so change could not be determined; excluded from meta-analysis.1 study · 29 participantsGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Interventions for managing oral submucous fibrosis
2024 · Cochrane All outcomes
2022-09Not listedNot assessed

The same intervention and outcome, asked in another population or against another comparator.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.