Question · asked by 1 review

Ciclosporin rinse vs Placebo (vehicle cream): Pain reduction (participant-reported symptoms)

Population
People with erosive oral lichen planus
Intervention
Ciclosporin rinse
Comparison
Placebo (vehicle cream)
Outcome
Pain reduction (participant-reported symptoms)

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Ciclosporin rinse vs Placebo (vehicle)
Pain reduction (participant-reported symptoms) · People with erosive oral lichen planus
Interventions for erosive lichen planus affecting mucosal sites (2012) · Cochrane All outcomes
We were unable to extract data on participant-reported symptoms for Eisen 1990 because there was no breakdown of data for the ELP subgroup.1 study · 8 participantsGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Interventions for erosive lichen planus affecting mucosal sites
2012 · Cochrane All outcomes
2009-09Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.