Question · asked by 0 reviews
Low molecular weight heparin vs UFH: Major bleeding
- Population
- People with cancer with perioperative thromboprophylaxis
- Intervention
- Low molecular weight heparin
- Comparison
- UFH
- Outcome
- Major bleeding
LMWH showed no clear difference in major bleeding compared with UFH (moderate certainty).
What each review found
Current versions onlyNo studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 2 · 100%High 0 · 0%
| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
LMWH vs UFH Major bleeding · patients with perioperative thromboprophylaxis in patients with cancer LMWH showed no clear difference in major bleeding compared with UFH (moderate certainty). Anticoagulation for perioperative thromboprophylaxis in people with cancer (2014) · Cochrane Headline outcomes onlyearlier version CD009447.PUB2, superseded | RR 0.85 [0.52, 1.37] | 8 studies · 3533 participants | Moderate |
LMWH vs UFH Major bleeding · patients with perioperative thromboprophylaxis in patients with cancer LMWH showed no clear difference in major bleeding compared with UFH (moderate certainty). Anticoagulation for perioperative thromboprophylaxis in people with cancer (2011) · Cochrane Headline outcomes onlyearlier version CD009447, superseded | RR 0.84 [0.52, 1.36] | 7 studies · 3441 participants | Moderate |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Anticoagulation for perioperative thromboprophylaxis in people with cancer 2018 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
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How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.