Question · asked by 1 review

Summary of findings: levofloxacin for inhalation solution vs tobramycin: Adverse events: number of treatment‐related adverse events

Population
adults and children aged over 12 with CF and P aeruginosa
Intervention
Summary of findings: levofloxacin for inhalation solution
Comparison
tobramycin
Outcome
Adverse events: number of treatment‐related adverse events

What each review found

Current versions only
No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 2 · 100%
FindingEffectStudiesGRADE certainty
Summary of findings: levofloxacin for inhalation solution vs tobramycin
Adverse events: number of treatment‐related adverse events · adults and children aged over 12 with CF and P aeruginosa
Inhaled anti‐pseudomonal antibiotics for long‐term therapy in cystic fibrosis (2022) · Cochrane Headline outcomes only
no estimate extracted1 study · 282 participantsHigh
Summary of findings: levofloxacin for inhalation solution vs tobramycin
Adverse events: number of treatment‐related adverse events · adults and children aged over 12 with CF and P aeruginosa
Inhaled anti‐pseudomonal antibiotics for long‐term therapy in cystic fibrosis (2018) · Cochrane Headline outcomes onlyearlier version CD001021.PUB3, superseded
no estimate extracted1 study · 282 participantsHigh

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Inhaled anti‐pseudomonal antibiotics for long‐term therapy in cystic fibrosis
2022 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.