Antihypertensive drug therapy vs placebo: Number of cases of dementia Range of
It is very uncertain whether antihypertensive therapy changes number of cases of dementia Range of compared with placebo (very low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Antihypertensive therapy vs placebo Number of cases of dementia Range of · participants without prior cerebrovascular disease for prevention of cognitive impairment and dementia It is very uncertain whether antihypertensive therapy changes number of cases of dementia Range of compared with placebo (very low certainty). Pharmacological treatment of hypertension in people without prior cerebrovascular disease for the prevention… (2021) · Cochrane Headline outcomes only | OR 0.89 [0.72, 1.07] | 4 studies · 15427 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Pharmacological treatment of hypertension in people without prior cerebrovascular disease for the prevention of cognitive impairment and… 2021 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.