Question · asked by 1 review
Oral glucosamine hydrochloride/chondroitin sulphate vs placebo: Total pain rating index (McGill Pain Questionnaire)
- Population
- Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of minimum 3 months' duration
- Intervention
- Oral glucosamine hydrochloride/chondroitin sulphate
- Comparison
- placebo
- Outcome
- Total pain rating index (McGill Pain Questionnaire)
Oral glucosamine hydrochloride/chondroitin sulphate showed no clear difference in total pain rating index (McGill Pain Questionnaire) compared with placebo; GRADE not reported.
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Oral glucosamine hydrochloride/chondroitin sulphate vs Placebo Total pain rating index (McGill Pain Questionnaire) · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to… · 3 months Oral glucosamine hydrochloride/chondroitin sulphate showed no clear difference in total pain rating index (McGill Pain Questionnaire) compared with placebo; GRADE not reported. Pharmacological interventions for pain in patients with temporomandibular disorders (2010) · Cochrane All outcomes | MD 1.60 [-8.29, 11.49] | 1 study · 45 participants | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Pharmacological interventions for pain in patients with temporomandibular disorders 2010 · Cochrane All outcomes | 2010-08 | Not listed | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.