Question · asked by 1 review

Summary of findings: Single vs combination intravenous anti‐pseudomonal antibiotic therapy: Change in FEV1 % predicted at end of antibiotic course: absolute post‐treatment values

Summary of findings: single showed no clear difference in change in FEV1 % predicted at end of antibiotic course: absolute… compared with combination intravenous anti‐pseudomonal antibiotic therapy (low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Summary of findings: single vs combination intravenous anti‐pseudomonal antibiotic therapy
Change in FEV1 % predicted at end of antibiotic course: absolute post‐treatment values · children and adults with cystic fibrosis
Summary of findings: single showed no clear difference in change in FEV1 % predicted at end of antibiotic course: absolute… compared with combination intravenous anti‐pseudomonal antibiotic therapy (low certainty).
Single versus combination intravenous anti‐pseudomonal antibiotic therapy for people with cystic fibrosis (2021) · Cochrane Headline outcomes only
MD 5.252 studies · 93 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Single versus combination intravenous anti‐pseudomonal antibiotic therapy for people with cystic fibrosis
2021 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.