Question · asked by 1 review

Oral gabapentin vs placebo: Participants' assessment of global function (VAS)

Population
Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of minimum 3 months' duration
Intervention
Oral gabapentin
Comparison
placebo
Outcome
Participants' assessment of global function (VAS)

Oral gabapentin (anticonvulsant) showed no clear difference in participants' assessment of global function (VAS) compared with placebo; GRADE not reported.

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Oral gabapentin (anticonvulsant) vs Placebo
Participants' assessment of global function (VAS) · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to… · 12 weeks
Oral gabapentin (anticonvulsant) showed no clear difference in participants' assessment of global function (VAS) compared with placebo; GRADE not reported.
Pharmacological interventions for pain in patients with temporomandibular disorders (2010) · Cochrane All outcomes
MD -1.50 [-3.10, 0.10]1 study · 44 participantsGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Pharmacological interventions for pain in patients with temporomandibular disorders
2010 · Cochrane All outcomes
2010-08Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.