Question · asked by 1 review

Azithromycin vs cefaclor: Minor adverse events not leading to withdrawal of treatment

Population
bacterial boils (furuncles and carbuncles)
Intervention
Azithromycin
Comparison
cefaclor
Outcome
Minor adverse events not leading to withdrawal of treatment

It is very uncertain whether azithromycin changes minor adverse events not leading to withdrawal of treatment… compared with cefaclor (very low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Azithromycin vs cefaclor
Minor adverse events not leading to withdrawal of treatment (reported during 7 days of treatment) · bacterial boils (furuncles and carbuncles)
It is very uncertain whether azithromycin changes minor adverse events not leading to withdrawal of treatment… compared with cefaclor (very low certainty).
Interventions for bacterial folliculitis and boils (furuncles and carbuncles) (2021) · Cochrane Headline outcomes only
RR 1.26 [0.38, 4.17]2 studies · 2744 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Interventions for bacterial folliculitis and boils (furuncles and carbuncles)
2021 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.