Mucolytic vs placebo: Death during study period
Mucolytic showed no clear difference in death during study period compared with placebo (low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Mucolytic vs placebo Death during study period · patients with chronic bronchitis or chronic obstructive pulmonary disease Mucolytic showed no clear difference in death during study period compared with placebo (low certainty). Mucolytic agents versus placebo for chronic bronchitis or chronic obstructive pulmonary disease (2015) · Cochrane Headline outcomes onlyearlier version CD001287.PUB5, superseded | OR 1.03 [0.52, 2.03] | 8 studies · 2931 participants | Low |
Mucolytic vs placebo Death during study period · patients with chronic bronchitis or chronic obstructive pulmonary disease It is very uncertain whether mucolytic changes death during study period compared with placebo (very low certainty). Mucolytic agents versus placebo for chronic bronchitis or chronic obstructive pulmonary disease (2012) · Cochrane Headline outcomes onlyearlier version CD001287.PUB4, superseded | OR 0.75 [0.35, 1.64] | 6 studies · 1821 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Mucolytic agents versus placebo for chronic bronchitis or chronic obstructive pulmonary disease 2019 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.