Question · asked by 1 review

Ceftriaxone vs long‐acting (oily) Chloramphenicol compared: Clinical failure ‐ in all participants ‐ short term Composite clinical criteria10

Ceftriaxone showed no clear difference in clinical failure ‐ in all participants ‐ short term Composite… compared with long‐acting (oily) chloramphenicol (moderate certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Ceftriaxone vs long‐acting (oily) chloramphenicol
Clinical failure ‐ in all participants ‐ short term Composite clinical criteria10 · people suspected to have meningococcal disease (adults and children)
Ceftriaxone showed no clear difference in clinical failure ‐ in all participants ‐ short term Composite… compared with long‐acting (oily) chloramphenicol (moderate certainty).
Pre‐admission antibiotics for suspected cases of meningococcal disease (2017) · Cochrane Headline outcomes only
OR 0.83 [0.32, 2.15]1 study · 477 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Pre‐admission antibiotics for suspected cases of meningococcal disease
2017 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.