Question · asked by 1 review
Dental extraction protocol with plasma rich in growth factors (PRGF) inserted into the postextraction alveolus vs Standard dental extraction protocol without PRGF: Complications and side effects
- Population
- People with cancer treated with intravenous bisphosphonates undergoing dental extractions (at risk of MRONJ)
- Intervention
- Dental extraction protocol with plasma rich in growth factors (PRGF) inserted into the postextraction alveolus
- Comparison
- Standard dental extraction protocol without PRGF
- Outcome
- Complications and side effects
What each review found
Current versions onlyNo studies found 0 · 0%GRADE not reported 2 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Dental extraction protocol with plasma rich in growth factors (PRGF) inserted into the postextraction alveolus vs Standard dental extraction protocol without PRGF Rate of complications and side effects of the intervention · People with cancer treated with intravenous bisphosphonates undergoing dental extractions (at risk of MRONJ) · 24 to 60 months Interventions for managing medication‐related osteonecrosis of the jaw (2022) · Cochrane All outcomes | No intraoperative complications were observed in either of the groups. | 1 study · 176 participants | GRADE not reported |
Dental extraction protocol with plasma rich in growth factors (PRGF) inserted into the postextraction alveolus vs Standard dental extraction protocol without PRGF Rate of complications and side effects of the intervention · People with cancer treated with intravenous bisphosphonates undergoing dental extractions (at risk of MRONJ) · 24 to 60 months Interventions for managing medication‐related osteonecrosis of the jaw (2017) · Cochrane All outcomesearlier version CD012432.PUB2, superseded | No intraoperative complications were observed in either of the groups. | 1 study · 176 participants | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Interventions for managing medication‐related osteonecrosis of the jaw 2022 · Cochrane All outcomes | 2021-06 | Not listed | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.