Very early treatment vs expectant management: Neurodevelopmental outcomes (moderate/severe motor delay at 18 to 24 months)
Very early treatment showed no clear difference in neurodevelopmental outcomes (moderate/severe motor delay at 18 to 24… compared with expectant management (low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Very early treatment vs expectant management Neurodevelopmental outcomes (moderate/severe motor delay at 18 to 24 months) · preterm infants Very early treatment showed no clear difference in neurodevelopmental outcomes (moderate/severe motor delay at 18 to 24… compared with expectant management (low certainty). Early treatment versus expectant management of hemodynamically significant patent ductus arteriosus for… (2020) · Cochrane Headline outcomes only | RR 0.54 [0.05, 5.71] | 1 study · 79 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Early treatment versus expectant management of hemodynamically significant patent ductus arteriosus for preterm infants 2020 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.