Question · asked by 1 review

Metronidazole vs placebo: Proportion of participants with adverse event

Population
Participants with rosacea
Intervention
Metronidazole
Comparison
placebo
Outcome
Proportion of participants with adverse event

Metronidazole showed no clear difference in proportion of participants with adverse event compared with placebo (high certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Metronidazole vs placebo
Proportion of participants with adverse event · Participants with rosacea
Metronidazole showed no clear difference in proportion of participants with adverse event compared with placebo (high certainty).
Interventions for rosacea (2015) · Cochrane Headline outcomes only
RR 1.19 [0.94, 1.51]6 studies · 1773 participantsHigh

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Interventions for rosacea
2015 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.