NSAIDs vs opioid: Relief of pain
- Population
- women who have given birth vaginally, requiring analgesia for after‐birth pains.
- Intervention
- NSAIDs
- Comparison
- opioid
- Outcome
- Relief of pain
NSAID probably leads to higher adequate pain relief as reported by the woman (5 to 8 hours) compared with opioid (moderate certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
NSAID vs opioid Adequate pain relief as reported by the woman (5 to 8 hours) · women who have given birth vaginally, requiring analgesia for after‐birth pains. NSAID probably leads to higher adequate pain relief as reported by the woman (5 to 8 hours) compared with opioid (moderate certainty). Relief of pain due to uterine cramping/involution after birth (2020) · Cochrane Headline outcomes only | RR 1.33 [1.13, 1.57] | 5 studies · 560 participants | Moderate |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Relief of pain due to uterine cramping/involution after birth 2020 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- NSAIDs vs placebo · women who have given birth vaginally, requiring analgesia for after‐birth pains. · 1 review
- NSAIDs vs herbal analgesia · women who have given birth vaginally, requiring analgesia for after‐birth pains. · 1 review
- NSAIDs vs paracetamol · women with primary dysmenorrhoea · 1 review
- NSAIDs vs placebo · women with primary dysmenorrhoea · 1 review
- NSAIDs vs placebo · women with perineal pain in the early postpartum period · 0 reviews
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.