Question · asked by 1 review

Radioisotopes vs placebo: Pain relief ‐ Complete/Partial relief

Population
patients with metastatic bone pain
Intervention
Radioisotopes
Comparison
placebo
Outcome
Pain relief ‐ Complete/Partial relief

Radioisotopes probably leads to higher pain relief ‐ Complete/Partial relief compared with placebo (moderate certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Radioisotopes vs Placebo
Pain relief ‐ Complete/Partial relief · patients with metastatic bone pain
Radioisotopes probably leads to higher pain relief ‐ Complete/Partial relief compared with placebo (moderate certainty).
Radioisotopes for metastatic bone pain (2011) · Cochrane Headline outcomes only
RR 1.72 [1.13, 2.63]3 studies · 119 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Radioisotopes for metastatic bone pain
2011 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.