Question · asked by 1 review

Summary of findings: repaglinide vs insulin: HbA1c (glycated haemoglobin), change

Summary of findings: repaglinide showed no clear difference in hbA1c (%) change from baseline compared with insulin (high certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Summary of findings: repaglinide vs insulin
HbA1c (%) change from baseline · children over 12 and adults with CFRD
Summary of findings: repaglinide showed no clear difference in hbA1c (%) change from baseline compared with insulin (high certainty).
Drug treatments for managing cystic fibrosis‐related diabetes (2020) · Cochrane Headline outcomes only
MD 0.31 study · 67 participantsHigh

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Drug treatments for managing cystic fibrosis‐related diabetes
2020 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.