Question · asked by 1 review

Proton pump inhibitors plus prokinetics vs prokinetics: Global symptoms of dyspepsia

Proton pump inhibitors plus prokinetics showed no clear difference in global symptoms of dyspepsia compared with prokinetics alone (moderate certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Proton pump inhibitors plus prokinetics vs prokinetics alone
Global symptoms of dyspepsia · adults with functional dyspepsia
Proton pump inhibitors plus prokinetics showed no clear difference in global symptoms of dyspepsia compared with prokinetics alone (moderate certainty).
Proton pump inhibitors for functional dyspepsia (2017) · Cochrane Headline outcomes only
RR 0.85 [0.68, 1.08]2 studies · 407 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Proton pump inhibitors for functional dyspepsia
2017 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.