Question · asked by 1 review
38% SDF (applied every 6 or 12 months) vs 12% SDF solution (applied annually): Caries arrest
- Population
- Children (age 1-10 years) with active cavitated dentin caries lesions in primary molars
- Intervention
- 38% SDF (applied every 6 or 12 months)
- Comparison
- 12% SDF solution (applied annually)
- Outcome
- Caries arrest
38% SDF arrested more caries than 12% SDF (pooled ES 0.37, 95% CI 0.27-0.47; single study; ungraded).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
38% SDF (applied every 6 or 12 months) vs 12% SDF Caries arrest · Children (age 1-10 years) with active cavitated dentin caries lesions in primary molars · 24-30 months, Pediatric dental care in hospital, community/school and outpatient settings (Saudi Arabia, China, India, Brazil, Spain), SDF application frequency: variable (Fung 2018; 38% vs 12% SDF) 38% SDF arrested more caries than 12% SDF (pooled ES 0.37, 95% CI 0.27-0.47; single study; ungraded). Silver Diamine Fluoride (SDF) Efficacy in Arresting Cavitated Caries Lesions in Primary Molars: A Systematic… (2022) All outcomes | ES 0.37 [0.27, 0.47] | 1 study · 888 participants | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Silver Diamine Fluoride (SDF) Efficacy in Arresting Cavitated Caries Lesions in Primary Molars: A Systematic Review and Metanalysis. 2022 All outcomes | 10 January 2022 (databases searched from inception to 10 January 2022) | 16 | Critically Low / Critically Low |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.