Question · asked by 1 review

PET-CT following chemoradiotherapy (neck dissection only if no/incomplete response) vs Planned neck dissection before or after chemoradiotherapy: Adverse events associated with treatment

Population
Adults with oral cavity or oropharyngeal cancer with nodal disease (stage N2 or N3)
Intervention
PET-CT following chemoradiotherapy (neck dissection only if no/incomplete response)
Comparison
Planned neck dissection before or after chemoradiotherapy
Outcome
Adverse events associated with treatment

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
PET-CT following chemoradiotherapy (neck dissection only if no/incomplete response) vs Planned neck dissection before or after chemoradiotherapy
Adverse events associated with treatment · Adults with oral cavity or oropharyngeal cancer with nodal disease (stage N2 or N3)
Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment (2023) · Cochrane All outcomes
Adverse events: 22 surgical complications in the PET-CT group vs 83 in the planned-surgery group (Mehanna 2017).1 study · 564 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment
2023 · Cochrane All outcomes
2022-02Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.