Question · asked by 1 review
Dornase alfa vs after airway clearance techniques: Adverse effects
- Population
- adults and children with cystic fibrosis
- Intervention
- Dornase alfa
- Comparison
- after airway clearance techniques
- Outcome
- Adverse effects
What each review found
Current versions onlyNo studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Inhalation of dornase alfa before vs after airway clearance techniques Adverse effects · adults and children with cystic fibrosis Timing of dornase alfa inhalation for cystic fibrosis (2021) · Cochrane Headline outcomes only | no estimate extracted | 102 participants | Very low |
Inhalation of dornase alfa before vs after airway clearance techniques Adverse effects · adults and children with cystic fibrosis Timing of dornase alfa inhalation for cystic fibrosis (2018) · Cochrane Headline outcomes onlyearlier version CD007923.PUB5, superseded | no estimate extracted | 102 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Timing of dornase alfa inhalation for cystic fibrosis 2021 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.