Question · asked by 1 review
Zinc chloride without sodium chlorite mouthrinse (Breath Rx containing cetylpyridinium chloride) vs Control mouthrinse (containing neither zinc chloride nor sodium chlorite): Volatile sulphur compounds (VSC), halimeter
- Population
- Adults over 18 years with a clinical or self-assessed diagnosis of halitosis, without significant comorbidity (e.g. diabetes) or refractory/severe chronic periodontal disease
- Intervention
- Zinc chloride without sodium chlorite mouthrinse (Breath Rx containing cetylpyridinium chloride)
- Comparison
- Control mouthrinse (containing neither zinc chloride nor sodium chlorite)
- Outcome
- Volatile sulphur compounds (VSC), halimeter
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Zinc chloride without sodium chlorite mouthrinse (Breath Rx containing cetylpyridinium chloride) vs Control mouthrinse (containing neither zinc chloride nor sodium chlorite) Halimeter-assessed volatile sulphur compounds (VSC) · Adults over 18 years with a clinical or self-assessed diagnosis of halitosis, without significant comorbidity (e.g.… · 4 weeks Mouthrinses for the treatment of halitosis (2008) · Cochrane All outcomes | Codipilly 2004: reported VSC reduction from baseline for zinc chloride minus sodium chlorite (Breath Rx containing cetylpyridinium chloride): 38% (P < 0.05) at 2 weeks, versus a control containing neither zinc chloride… | 1 study | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Mouthrinses for the treatment of halitosis 2008 · Cochrane All outcomes | 2008-08 | Not listed | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.