Question · asked by 1 review

Any supplements containing iron and folic acid vs same supplements without iron nor folic acid (no iron nor folic acid or placebo): Side effects (any reported throughout the intervention period) (ALL)

(Maternal outcomes) Any supplements containing iron and folic acid probably leads to higher side effects (any reported throughout the intervention period) (ALL) compared with same supplements without iron nor folic acid (no iron nor folic acid… (moderate certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
(Maternal outcomes) Any supplements containing iron and folic acid vs same supplements without iron nor folic acid (no iron nor folic acid or placebo)
Side effects (any reported throughout the intervention period) (ALL) · Pregnant women of any gestational age and parity
(Maternal outcomes) Any supplements containing iron and folic acid probably leads to higher side effects (any reported throughout the intervention period) (ALL) compared with same supplements without iron nor folic acid (no iron nor folic acid… (moderate certainty).
Daily oral iron supplementation during pregnancy (2015) · Cochrane Headline outcomes only
RR 44.32 [2.77, 709.09]1 study · 456 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Daily oral iron supplementation during pregnancy
2015 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.