Question · asked by 1 review

Anticholinergic and short‐acting beta2‐agonists vs B2‐agonists alone: Hospital admissions

Anticholinergic and short‐acting beta2‐agonists leads to lower primary outcome: hospital admissions hospital admissions compared with beta2‐agonists alone (all protocols) (high certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Anticholinergic and short‐acting beta2‐agonists vs beta2‐agonists alone (all protocols)
Primary outcome: hospital admissions hospital admissions · children with initial treatment of acute asthma
Anticholinergic and short‐acting beta2‐agonists leads to lower primary outcome: hospital admissions hospital admissions compared with beta2‐agonists alone (all protocols) (high certainty).
Combined inhaled anticholinergics and short‐acting beta₂‐agonists for initial treatment of acute asthma in… (2013) · Cochrane Headline outcomes only
RR 0.73 [0.63, 0.85]19 studies · 2497 participantsHigh

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Combined inhaled anticholinergics and short‐acting beta₂‐agonists for initial treatment of acute asthma in children
2013 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.