Question · asked by 1 review
Dental caries vs Caries-free status: CA VI concentration
- Population
- Individuals assessed for dental caries (cases with caries/high caries vs. caries-free or low/very-low-caries controls)
- Intervention
- Dental caries
- Comparison
- Caries-free status
- Outcome
- CA VI concentration
CA VI concentration was lower in participants with caries (SMD -0.66, 95% CI -1.00 to -0.32; 2 studies, 141 participants); GRADE was not reported.
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Dental caries vs Caries-free CA VI concentration · Participants with dental caries and caries-free participants · Brazil CA VI concentration was lower in participants with caries (SMD -0.66, 95% CI -1.00 to -0.32; 2 studies, 141 participants); GRADE was not reported. Associations of the activity and concentration of carbonic anhydrase VI with susceptibility to dental… (2023) All outcomes | SMD -0.66 [-1.00, -0.32] | 2 studies · 141 participants | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Associations of the activity and concentration of carbonic anhydrase VI with susceptibility to dental caries: A systematic review and… 2023 All outcomes | Inception to August 2022 | 10 | Not applicable |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.