Question · asked by 1 review

Laser fluorescence (LF; DIAGNOdent) vs Reference standard (histology, excavation, or enhanced visual examination): Diagnostic accuracy (sensitivity, specificity) - not pooled

Population
Permanent and primary teeth, smooth surfaces, with suspected caries lesions
Intervention
Laser fluorescence (LF; DIAGNOdent)
Comparison
Reference standard (histology, excavation, or enhanced visual examination)
Outcome
Diagnostic accuracy (sensitivity, specificity) - not pooled

Only 2 LF studies assessed smooth surfaces, so no pooled estimate was possible; both reported higher specificity than sensitivity (evidence not graded).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Laser fluorescence (LF; DIAGNOdent) vs Reference standard (histological examination, operative intervention, or other/visual examination)
Diagnostic accuracy (sensitivity, specificity) - not pooled · Permanent and primary teeth, smooth surfaces, with suspected caries lesions · Initial and more advanced caries lesions thresholds, Permanent and primary teeth; smooth surfaces
Only 2 LF studies assessed smooth surfaces, so no pooled estimate was possible; both reported higher specificity than sensitivity (evidence not graded).
Fluorescence-based methods for detecting caries lesions: systematic review, meta-analysis and sources of… (2013) All outcomes
Only two included studies assessed smooth surfaces (both used LF; one permanent, one primary); no meta-analysis was possible. Both reported specificity higher than sensitivity at both thresholds.2 studiesGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Fluorescence-based methods for detecting caries lesions: systematic review, meta-analysis and sources of heterogeneity.
2013 All outcomes
19 June 201275Not applicable
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.