Question · asked by 1 review

Belimumab 10 mg/kg vs placebo: Number of participants who died during the study

Belimumab 10 mg/kg showed no clear difference in number of participants who died during the study compared with placebo (low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Belimumab 10 mg/kg vs placebo
Number of participants who died during the study · people with active systemic lupus erythematosus (but not active nephritis or active central nervous system involvement)
Belimumab 10 mg/kg showed no clear difference in number of participants who died during the study compared with placebo (low certainty).
Belimumab for systemic lupus erythematosus (2021) · Cochrane Headline outcomes only
Peto OR 1.15 [0.41, 3.25]6 studies · 2917 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Belimumab for systemic lupus erythematosus
2021 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.