Question · asked by 1 review
30% SDF solution (once weekly for 3 weeks) vs Fluoride varnish: Arrest of advanced cavitated carious lesions on any coronal surface
- Population
- Preschool children with advanced cavitated carious lesions on any coronal surface (primary teeth)
- Intervention
- 30% SDF solution (once weekly for 3 weeks)
- Comparison
- Fluoride varnish
- Outcome
- Arrest of advanced cavitated carious lesions on any coronal surface
30% SDF solution (once weekly for 3 weeks) probably did not differ from 5% NaF varnish (once weekly for 3 weeks) for arrest or reversal of cavitated coronal carious lesions (RR 0.97, 95% CI 0.8 to 1.18; moderate certainty).
What each review found
Include earlier review versionsNo studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 1 · 33.3%High 2 · 66.7%
| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
30% SDF solution (once weekly for 3 weeks) vs 5% NaF varnish (once weekly for 3 weeks) Arrest of advanced cavitated carious lesions on any coronal surface · Preschool children with advanced cavitated carious lesions on any coronal surface (primary teeth) · 30 mo, Dental practice (professionally applied or prescribed nonrestorative caries treatments; parallel and split-mouth RCTs) 30% SDF solution (once weekly for 3 weeks) probably did not differ from 5% NaF varnish (once weekly for 3 weeks) for arrest or reversal of cavitated coronal carious lesions (RR 0.97, 95% CI 0.8 to 1.18; moderate certainty). Nonrestorative Treatments for Caries: Systematic Review and Network Meta-analysis. (2019) All outcomes | RR 0.97 [0.8, 1.18] | 1 study · 309 participants | Moderate |
30% SDF solution (once weekly for 3 weeks) vs 5% NaF varnish (once weekly for 3 weeks) Arrest of advanced cavitated carious lesions on any coronal surface · Preschool children with advanced cavitated carious lesions on any coronal surface (primary teeth) · 18 mo, Dental practice (professionally applied or prescribed nonrestorative caries treatments; parallel and split-mouth RCTs) 30% SDF solution (once weekly for 3 weeks) was more effective than 5% NaF varnish (once weekly for 3 weeks) for arrest or reversal of cavitated coronal carious lesions (RR 1.3, 95% CI 1.07 to 1.57; high certainty). Nonrestorative Treatments for Caries: Systematic Review and Network Meta-analysis. (2019) All outcomes | RR 1.3 [1.07, 1.57] | 1 study · 309 participants | High |
30% SDF solution (once weekly for 3 weeks) vs 5% NaF varnish (once weekly for 3 weeks) Arrest of advanced cavitated carious lesions on any coronal surface · Preschool children with advanced cavitated carious lesions on any coronal surface (primary teeth) · 12 mo, Dental practice (professionally applied or prescribed nonrestorative caries treatments; parallel and split-mouth RCTs) 30% SDF solution (once weekly for 3 weeks) was more effective than 5% NaF varnish (once weekly for 3 weeks) for arrest or reversal of cavitated coronal carious lesions (RR 2.08, 95% CI 1.59 to 2.71; high certainty). Nonrestorative Treatments for Caries: Systematic Review and Network Meta-analysis. (2019) All outcomes | RR 2.08 [1.59, 2.71] | 1 study · 309 participants | High |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Nonrestorative Treatments for Caries: Systematic Review and Network Meta-analysis. 2019 All outcomes | June 2017 | 54 | Critically Low / Critically Low |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.