Modified bovine minced lung surfactant extract vs porcine minced lung surfactant extract: Severe intraventricular hemorrhage in infants who received neuroimaging
It is very uncertain whether modified bovine minced lung surfactant extract changes severe intraventricular hemorrhage in infants who received… compared with porcine minced lung surfactant extract (very low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Modified bovine minced lung surfactant extract vs porcine minced lung surfactant extract Severe intraventricular hemorrhage in infants who received neuroimaging · Preterm infants for treatment of RDS It is very uncertain whether modified bovine minced lung surfactant extract changes severe intraventricular hemorrhage in infants who received… compared with porcine minced lung surfactant extract (very low certainty). Comparison of animal‐derived surfactants for the prevention and treatment of respiratory distress syndrome… (2015) · Cochrane Headline outcomes only | RR 1.28 [0.83, 1.97] | 7 studies · 705 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Comparison of animal‐derived surfactants for the prevention and treatment of respiratory distress syndrome in preterm infants 2015 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.