Question

Metformin vs clomiphene: Clinical pregnancy rate per woman aParticipants with BMI ≥ 30 kg/m2

Population
women with polycystic ovary syndrome
Intervention
Metformin
Comparison
clomiphene
Outcome
Clinical pregnancy rate per woman aParticipants with BMI ≥ 30 kg/m2

Reviews word the same question differently. Two decision models (TypeSafe's Jev and Liquid AI's d1) judged each wording of the population, intervention, comparator and outcome against the others, and rows count as this question only when both agree on all four. Timing, setting and subgroup never split a question: they are shown on each row.

Reviews
2
current versions
Answers
2
all review versions
GRADE rated
2
answers with a certainty rating
Included studies linked
0
full-text reviews only
No studies 0 · 0%Ungraded 0 · 0%Very low 1 · 50%Low 1 · 50%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

How each review answered it

Current versions only
QuestionEffectEvidenceStatus / GRADE
Metformin vs clomiphene citrate
Clinical pregnancy rate per woman aParticipants with BMI ≥ 30 kg/m2 · women with polycystic ovary syndrome
Metformin for ovulation induction (excluding gonadotrophins) in women with polycystic ovary syndrome (2019) · Cochrane
OR 0.34 [0.21, 0.55]2 studies · 500 participantsLow
Metformin vs clomiphene citrate
Clinical pregnancy rate per woman Participants with BMI ≥ 30 kg/m2a · women with polycystic ovary syndrome
Insulin‐sensitising drugs (metformin, rosiglitazone, pioglitazone, D‐chiro‐inositol) for women with… (2017) · Cochrane
OR 0.34 [0.21, 0.55]2 studies · 500 participantsVery low

Trials and studies behind the answers

The primary studies that full-text reviews tie to these outcomes. Reviews from the Summary of Findings tier list no included studies here, and trials have not yet been matched to questions on their own, so this list is incomplete.

No included studies are linked to these answers yet.