Question · asked by 1 review

Loratadine 10 mg vs mizolastine 10 mg: Proportion of participants with at least 50% improvement in QoL: intermediate‐term duration of intervention Symptom score reducing index (SSRI)

It is very uncertain whether loratadine 10 mg changes proportion of participants with at least 50% improvement in QoL:… compared with mizolastine 10 mg (very low certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Loratadine 10 mg vs mizolastine 10 mg
Proportion of participants with at least 50% improvement in QoL: intermediate‐term duration of intervention Symptom score reducing index (SSRI) · patients with chronic spontaneous urticaria
It is very uncertain whether loratadine 10 mg changes proportion of participants with at least 50% improvement in QoL:… compared with mizolastine 10 mg (very low certainty).
H1‐antihistamines for chronic spontaneous urticaria (2014) · Cochrane Headline outcomes only
RR 3.21 [0.32, 32.33]2 studies · 252 participantsVery low

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
H1‐antihistamines for chronic spontaneous urticaria
2014 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.