Buprenorphine vs adrenergic agonist: Number experiencing adverse effects
Buprenorphine showed no clear difference in number experiencing adverse effects compared with adrenergic agonists (low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Buprenorphine vs adrenergic agonists Number experiencing adverse effects · patients with the management of opioid withdrawal Buprenorphine showed no clear difference in number experiencing adverse effects compared with adrenergic agonists (low certainty). Buprenorphine for managing opioid withdrawal (2009) · Cochrane Headline outcomes onlyearlier version CD002025.PUB4, superseded | RR 0.97 [0.76, 1.23] | 2 studies · 458 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Buprenorphine for managing opioid withdrawal 2017 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.