Rotavac vs placebo: Severe cases of rotavirus diarrhoea
Rotavac probably leads to lower severe cases of rotavirus diarrhoea compared with placebo (moderate certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Rotavac vs placebo Severe cases of rotavirus diarrhoea · children Rotavac probably leads to lower severe cases of rotavirus diarrhoea compared with placebo (moderate certainty). Vaccines for preventing rotavirus diarrhoea: vaccines in use (2021) · Cochrane Headline outcomes only | RR 0.43 [0.3, 0.6] | 1 study · 6799 participants | Moderate |
Rotavac vs placebo Severe cases of rotavirus diarrhoea · children Rotavac probably leads to lower severe cases of rotavirus diarrhoea compared with placebo (moderate certainty). Vaccines for preventing rotavirus diarrhoea: vaccines in use (2021) · Cochrane Headline outcomes only | RR 0.46 [0.35, 0.6] | 1 study · 6541 participants | Moderate |
Rotavac vs placebo Severe cases of rotavirus diarrhoea · children Rotavac probably leads to lower severe cases of rotavirus diarrhoea compared with placebo (moderate certainty). Vaccines for preventing rotavirus diarrhoea: vaccines in use (2019) · Cochrane Headline outcomes onlyearlier version CD008521.PUB4, superseded | RR 0.43 [0.3, 0.6] | 1 study · 6799 participants | Moderate |
Rotavac vs placebo Severe cases of rotavirus diarrhoea · children Rotavac probably leads to lower severe cases of rotavirus diarrhoea compared with placebo (moderate certainty). Vaccines for preventing rotavirus diarrhoea: vaccines in use (2019) · Cochrane Headline outcomes onlyearlier version CD008521.PUB4, superseded | RR 0.46 [0.35, 0.6] | 1 study · 6541 participants | Moderate |
Rotavac vs placebo Severe cases of rotavirus diarrhoea · children Rotavac probably leads to lower severe cases of rotavirus diarrhoea compared with placebo (moderate certainty). Vaccines for preventing rotavirus diarrhoea: vaccines in use (2019) · Cochrane Headline outcomes onlyearlier version CD008521.PUB5, superseded | RR 0.43 [0.3, 0.6] | 1 study · 6799 participants | Moderate |
Rotavac vs placebo Severe cases of rotavirus diarrhoea · children Rotavac probably leads to lower severe cases of rotavirus diarrhoea compared with placebo (moderate certainty). Vaccines for preventing rotavirus diarrhoea: vaccines in use (2019) · Cochrane Headline outcomes onlyearlier version CD008521.PUB5, superseded | RR 0.46 [0.35, 0.6] | 1 study · 6541 participants | Moderate |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Vaccines for preventing rotavirus diarrhoea: vaccines in use 2021 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.