Question · asked by 1 review
ASENAPINE vs placebo: Global state: No clinically important change (as defined by the original studies)
- Population
- adults with schizophrenia
- Intervention
- ASENAPINE
- Comparison
- placebo
- Outcome
- Global state: No clinically important change (as defined by the original studies)
ASENAPINE may leads to lower global state: No clinically important change CGI‐I compared with PLACEBO (low certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
ASENAPINE vs PLACEBO Global state: No clinically important change CGI‐I · adults with schizophrenia ASENAPINE may leads to lower global state: No clinically important change CGI‐I compared with PLACEBO (low certainty). Asenapine versus placebo for schizophrenia (2015) · Cochrane Headline outcomes only | RR 0.81 [0.68, 0.97] | 1 study · 336 participants | Low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Asenapine versus placebo for schizophrenia 2015 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.