Intratympanic plus systemic corticosteroids (combined therapy) vs systemic corticosteroids alone: Proportion of patients whose hearing is improved
- Population
- sudden sensorineural hearing loss
- Intervention
- Intratympanic plus systemic corticosteroids (combined therapy)
- Comparison
- systemic corticosteroids alone
- Outcome
- Proportion of patients whose hearing is improved
It is very uncertain whether intratympanic plus systemic corticosteroids (combined therapy) changes proportion of patients whose hearing is improved compared with systemic corticosteroids alone (very low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Intratympanic plus systemic corticosteroids (combined therapy) vs systemic corticosteroids alone Proportion of patients whose hearing is improved · sudden sensorineural hearing loss It is very uncertain whether intratympanic plus systemic corticosteroids (combined therapy) changes proportion of patients whose hearing is improved compared with systemic corticosteroids alone (very low certainty). Intratympanic corticosteroids for sudden sensorineural hearing loss (2022) · Cochrane Headline outcomes only | RR 1.27 [1.15, 1.41] | 10 studies · 788 participants | Very low |
Intratympanic plus systemic corticosteroids (combined therapy) vs systemic corticosteroids alone Proportion of patients whose hearing is improved · sudden sensorineural hearing loss It is very uncertain whether intratympanic plus systemic corticosteroids (combined therapy) changes proportion of patients whose hearing is improved compared with systemic corticosteroids alone (very low certainty). Intratympanic corticosteroids for sudden sensorineural hearing loss (2022) · Cochrane Headline outcomes only | RR 2.24 [1.1, 4.55] | 1 study · 76 participants | Very low |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Intratympanic corticosteroids for sudden sensorineural hearing loss 2022 · Cochrane Headline outcomes only | Not reported | Not extracted | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.