Question · asked by 1 review
Ciclosporin rinse vs Placebo (vehicle cream): Investigator‐ or physician‐rated global assessment of disease severity
- Population
- People with erosive oral lichen planus
- Intervention
- Ciclosporin rinse
- Comparison
- Placebo (vehicle cream)
- Outcome
- Investigator‐ or physician‐rated global assessment of disease severity
Ciclosporin rinse led to lower physician Global Assessment (severity of disease) compared with placebo (vehicle); GRADE not reported.
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Ciclosporin rinse vs Placebo (vehicle) Physician Global Assessment (severity of disease) · People with erosive oral lichen planus Ciclosporin rinse led to lower physician Global Assessment (severity of disease) compared with placebo (vehicle); GRADE not reported. Interventions for erosive lichen planus affecting mucosal sites (2012) · Cochrane All outcomes | MD -1.40 [-1.86, -0.94] | 1 study · 8 participants | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Interventions for erosive lichen planus affecting mucosal sites 2012 · Cochrane All outcomes | 2009-09 | Not listed | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.