Question · asked by 1 review

Angiotensin receptor blockers (ARBs) vs placebo or no treatment: All‐cause mortality (RR)

Angiotensin receptor blockers (ARBs) showed no clear difference in all‐cause mortality (RR) compared with placebo or no treatment (high certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Angiotensin receptor blockers (ARBs) vs placebo or no treatment
All‐cause mortality (RR) · patients with chronic heart failure with preserved ejection fraction
Angiotensin receptor blockers (ARBs) showed no clear difference in all‐cause mortality (RR) compared with placebo or no treatment (high certainty).
Beta‐blockers and inhibitors of the renin‐angiotensin aldosterone system for chronic heart failure with… (2021) · Cochrane Headline outcomes only
RR 1.01 [0.92, 1.11]4 studies · 7964 participantsHigh
ARB vs placebo or no treatment
All‐cause mortality (RR) · chronic heart failure with preserved ejection fraction
ARB showed no clear difference in all‐cause mortality (RR) compared with placebo or no treatment (high certainty).
Beta‐blockers and inhibitors of the renin‐angiotensin aldosterone system for chronic heart failure with… (2018) · Cochrane Headline outcomes onlyearlier version CD012721.PUB2, superseded
RR 1.01 [0.92, 1.11]4 studies · 7964 participantsHigh

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Beta‐blockers and inhibitors of the renin‐angiotensin aldosterone system for chronic heart failure with preserved ejection fraction
2021 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.