Question · asked by 1 review

Omega‐3 vs placebo: Any adverse event (combined: diarrhoea, urinary tract infection, falls, dizziness, agitations)

Omega‐3 PUFA supplements showed no clear difference in any adverse event (combined: diarrhoea, urinary tract infection,… compared with placebo (moderate certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Omega‐3 PUFA supplements vs placebo
Any adverse event (combined: diarrhoea, urinary tract infection, falls, dizziness, agitations) · people with mild to moderate Alzheimer's disease
Omega‐3 PUFA supplements showed no clear difference in any adverse event (combined: diarrhoea, urinary tract infection,… compared with placebo (moderate certainty).
Omega‐3 fatty acids for the treatment of dementia (2016) · Cochrane Headline outcomes only
RR 1.02 [0.95, 1.1]1 study · 402 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Omega‐3 fatty acids for the treatment of dementia
2016 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.