440 to 550 ppm F toothpaste vs Non-fluoride (0 ppm F) placebo toothpaste: Caries increment, surface index D(M)FS
- Population
- Children and adolescents with immature permanent dentition (aged 5 to 16 years at study start)
- Intervention
- 440 to 550 ppm F toothpaste
- Comparison
- Non-fluoride (0 ppm F) placebo toothpaste
- Outcome
- Caries increment, surface index D(M)FS
440 to 550 ppm F toothpaste showed no clear difference in caries increment, surface index D(M)FS compared with non-fluoride (0 ppm F) placebo toothpaste (low certainty).
What each review found
Current versions only| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
440 to 550 ppm F toothpaste vs Non-fluoride (0 ppm F) placebo toothpaste Caries increment, surface index D(M)FS · Children and adolescents with immature permanent dentition (aged 5 to 16 years at study start) · Closest to 36 months 440 to 550 ppm F toothpaste showed no clear difference in caries increment, surface index D(M)FS compared with non-fluoride (0 ppm F) placebo toothpaste (low certainty). Fluoride toothpastes of different concentrations for preventing dental caries (2019) · Cochrane All outcomes | SMD -0.12 [-0.31, 0.07] | 2 studies | Low |
440 to 550 ppm F toothpaste vs Non-fluoride (0 ppm F) placebo toothpaste Caries increment, surface index D(M)FS · Children and adolescents with immature permanent dentition (aged 5 to 16 years at study start) · Nearest to 3 years (closest to 36 months) 440 to 550 ppm F toothpaste showed no clear difference in caries increment, surface index D(M)FS compared with non-fluoride (0 ppm F) placebo toothpaste; GRADE not reported. Fluoride toothpastes of different concentrations for preventing dental caries (2010) · Cochrane All outcomesearlier version CD007868.PUB2, superseded | SMD -0.17 [-0.33, 0.0] | Not reported | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Fluoride toothpastes of different concentrations for preventing dental caries 2019 · Cochrane All outcomes | 2018-08 | Not listed | Not assessed |
Related questions
The same intervention and outcome, asked in another population or against another comparator.
- 440 to 550 ppm F toothpaste vs 250 ppm F toothpaste · Children and adolescents with immature permanent dentition (aged 5 to 16 years at study… · 1 review
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.