Question · asked by 1 review
38% silver diamine fluoride vs No treatment / other preventive agents (GIC, 5% NaF varnish): Caries arrest
- Population
- Children with dentine carious lesions (ICDAS 4-5) in primary teeth
- Intervention
- 38% silver diamine fluoride
- Comparison
- No treatment / other preventive agents (GIC, 5% NaF varnish)
- Outcome
- Caries arrest
A second meta-analysis reported odds ratios of 2.44 to 3.63 favouring 38% SDF over fluoride varnish/water for caries arrest (ungraded).
What each review found
Current versions onlyNo studies found 0 · 0%GRADE not reported 2 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
38% silver diamine fluoride (SDF) vs No treatment / other preventive agents (GIC, 5% NaF varnish) Caries arrest · Children with dentine carious lesions (ICDAS 4-5) in primary teeth · 18-30 months, 38% SDF vs 5% NaF varnish/water (Trieu et al. 2019 meta-analysis) A second meta-analysis reported odds ratios of 2.44 to 3.63 favouring 38% SDF over fluoride varnish/water for caries arrest (ungraded). Minimal intervention dentistry for managing carious lesions into dentine in primary teeth: an umbrella review. (2022) All outcomes | OR (caries arrest) OR 2.44-3.63 (range); 2.44 = Chu estimate including 30% SDF | 3 studies | GRADE not reported |
38% silver diamine fluoride (SDF) vs No treatment / other preventive agents (GIC, 5% NaF varnish) Caries arrest · Children with dentine carious lesions (ICDAS 4-5) in primary teeth · 6-48 months, Pooled caries-arrest proportion (Gao et al. 2016 meta-analysis) One meta-analysis reported an overall caries-arrest proportion of 81% (95% CI 68-89%) for 38% SDF in primary teeth (ungraded). Minimal intervention dentistry for managing carious lesions into dentine in primary teeth: an umbrella review. (2022) All outcomes | Proportion (caries arrest) 81 [68, 89] | 12 studies | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Minimal intervention dentistry for managing carious lesions into dentine in primary teeth: an umbrella review. 2022 All outcomes | August 2020 | 35 | Low / Low |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.