Question · asked by 1 review

Cerebrolysin or Cerebrolysin‐like agents vs placebo: SAEs

Cerebrolysin or Cerebrolysin‐like agents showed no clear difference in total number of people with SAEs** compared with placebo (moderate certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Cerebrolysin or Cerebrolysin‐like agents vs placebo
Total number of people with SAEs** · people with acute ischaemic stroke
Cerebrolysin or Cerebrolysin‐like agents showed no clear difference in total number of people with SAEs** compared with placebo (moderate certainty).
Cerebrolysin for acute ischaemic stroke (2023) · Cochrane Headline outcomes only
RR 1.16 [0.81, 1.66]3 studies · 1335 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Cerebrolysin for acute ischaemic stroke
2023 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.