Question · asked by 1 review

Antibiotics vs placebo: FEV1

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Antibiotics vs placebo
FEV1 (mL) WMD of · Adults (aged 40 or over) with COPD presenting with 1 or more exacerbations in the previous year. The two larger…
Prophylactic antibiotic therapy for chronic obstructive pulmonary disease (COPD) (2018) · Cochrane Headline outcomes only
no estimate extracted6 studies · 658 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Prophylactic antibiotic therapy for chronic obstructive pulmonary disease (COPD)
2018 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.