Question · asked by 1 review

Rectal midazolam vs A different sedative agent: Behaviour

Population
Children and adolescents (0 to 16 years) needing dental treatment
Intervention
Rectal midazolam
Comparison
A different sedative agent
Outcome
Behaviour

What each review found

Current versions only
No studies found 0 · 0%GRADE not reported 3 · 75%Very low 1 · 25%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
FindingEffectStudiesGRADE certainty
Rectal midazolam vs A different sedative agent
Behaviour · Children and adolescents (0 to 16 years) needing dental treatment
Sedation of children undergoing dental treatment (2018) · Cochrane All outcomes
Any behavioural score - Rectal midazolam versus (other sedatives): 90 (1); VERY LOW1 study · 90 participantsVery low
Rectal midazolam vs A different sedative agent
Behaviour · Children and adolescents (0 to 16 years) needing dental treatment
Sedation of children undergoing dental treatment (2012) · Cochrane All outcomesearlier version CD003877.PUB4, superseded
Jensen 1999 (rectal diazepam 0.7 mg/kg vs rectal midazolam 0.3 mg/kg): significant difference favouring diazepam at 1 hour. Narrative.1 studyGRADE not reported
Rectal midazolam vs A different sedative agent
Behaviour · Children and adolescents (0 to 16 years) needing dental treatment
Sedation of children undergoing dental treatment (2006) · Cochrane All outcomesearlier version CD003877.PUB3, superseded
Jensen 1999 (rectal midazolam vs rectal diazepam): more children agitated with diazepam at 1 hour; Lokken 1994 (rectal). Narrative.Not reportedGRADE not reported
Rectal midazolam vs A different sedative agent
Behaviour · Children and adolescents (0 to 16 years) needing dental treatment
Sedation of children undergoing dental treatment (2005) · Cochrane All outcomesearlier version CD003877.PUB2, superseded
Jensen 1999 (rectal midazolam vs rectal diazepam): more children agitated with diazepam at 1 hour. Narrative.Not reportedGRADE not reported

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Sedation of children undergoing dental treatment
2018 · Cochrane All outcomes
22 February 2018Not listedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.