Question · asked by 1 review
Povidone iodine rinse vs Saline rinse or placebo: Adverse effects
- Population
- Critically ill patients receiving mechanical ventilation in ICU
- Intervention
- Povidone iodine rinse
- Comparison
- Saline rinse or placebo
- Outcome
- Adverse effects
What each review found
Current versions onlyNo studies found 0 · 0%GRADE not reported 2 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Povidone iodine rinse vs Saline rinse or placebo Adverse effects · Critically ill patients receiving mechanical ventilation in ICU Oral hygiene care for critically ill patients to prevent ventilator‐associated pneumonia (2020) · Cochrane All outcomes | Adverse effects (Seguin 2014): no evidence of a difference in acute respiratory distress syndrome (RR 11.00, 95% CI 0.62 to 195.61), agitation and/or hypertension (RR 0.48, 95% CI 0.12 to 1.86), epistaxis (RR 0.14, 95%… | 1 study | GRADE not reported |
Povidone iodine rinse vs Saline rinse or placebo Adverse effects · Critically ill patients receiving mechanical ventilation in ICU Oral hygiene care for critically ill patients to prevent ventilator‐associated pneumonia (2016) · Cochrane All outcomesearlier version CD008367.PUB3, superseded | Adverse effects (Seguin 2014): no evidence of a difference in acute respiratory distress syndrome (RR 11.00, 95% CI 0.62 to 195.61), agitation and/or hypertension (RR 0.48, 95% CI 0.12 to 1.86), epistaxis (RR 0.14, 95%… | 1 study | GRADE not reported |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Oral hygiene care for critically ill patients to prevent ventilator‐associated pneumonia 2020 · Cochrane All outcomes | 2020-02 | Not listed | Not assessed |
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.