Question · asked by 1 review

Intermittent oral vs oral calcitriol: Fall in PTH

Intermittent oral showed no clear difference in fall in PTH compared with daily oral calcitriol (moderate certainty).

What each review found

Current versions only
FindingEffectStudiesGRADE certainty
Intermittent oral vs daily oral calcitriol
Fall in PTH · patients with bone disease in children with chronic kidney disease
Intermittent oral showed no clear difference in fall in PTH compared with daily oral calcitriol (moderate certainty).
Interventions for bone disease in children with chronic kidney disease (2010) · Cochrane Headline outcomes only
RR 0.88 [0.65, 1.19]1 study · 59 participantsModerate
Intermittent oral vs daily oral calcitriol
Fall in PTH % · patients with bone disease in children with chronic kidney disease
Interventions for bone disease in children with chronic kidney disease (2010) · Cochrane Headline outcomes only
no estimate extracted2 studies · 83 participantsModerate

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Interventions for bone disease in children with chronic kidney disease
2010 · Cochrane Headline outcomes only
Not reportedlist not extracted yetNot assessed

Studies behind the findings

None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.

How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.